Special Reviews

The Developing Synapse: Construction and Modulation of Synaptic Structures and Circuits

See allHide authors and affiliations

Science  25 Oct 2002:
Vol. 298, Issue 5594, pp. 770-776
DOI: 10.1126/science.1075510

You are currently viewing the abstract.

View Full Text

Log in to view the full text

Log in through your institution

Log in through your institution

Abstract

Synapse formation and stabilization in the vertebrate central nervous system is a dynamic process, requiring bi-directional communication between pre- and postsynaptic partners. Numerous mechanisms coordinate where and when synapses are made in the developing brain. This review discusses cellular and activity-dependent mechanisms that control the development of synaptic connectivity.

View Full Text