Protecting the Heart

+ See all authors and affiliations

Science  01 Nov 2002:
Vol. 298, Issue 5595, pp. 919k
DOI: 10.1126/science.298.5595.919k

Within the mitochondria of heart cells, ion channels control the flux of different ions and change the physiological status of the mitochondria, which in turn affect the relative health of the heart cell. Xu et al. (p. 1029) now describe the role of a calcium-activated potassium channel in the inner mitochondrial membrane of guinea-pig heart cells in protecting the cells from ischemia. A drug that opened the channel could protect the heart from infarction.

Related Content

Navigate This Article