A Tail of Transdifferentiation

Science  06 Dec 2002:
Vol. 298, Issue 5600, pp. 1901-1903
DOI: 10.1126/science.1079853

You are currently viewing the summary.

View Full Text

Via your Institution

Log in through your institution

Log in through your institution


Salamanders have the enviable ability of being able to regenerate an amputated limb or tail. These amphibians have proven to be a valuable model of tissue regeneration. In his Perspective, Stocum discusses the first unequivocal evidence that salamander tail regeneration involves the ability of neural precusor cells of ectodermal origin to transdifferentiate into mesodermal cell types.