News FocusMedicine

Tracing the Steps of Metastasis, Cancer's Menacing Ballet

Science  14 Feb 2003:
Vol. 299, Issue 5609, pp. 1002-1006
DOI: 10.1126/science.299.5609.1002

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Recent studies have unexpectedly found that a constellation of molecular signals in cancer cells and the patient's own body steer tumor cells, bit by bit, from the primary site to a new, ideal home. Large-scale gene studies are suggesting fundamental differences between such metastatic cells and other cancer cells. Researchers are also taking a deeper look at electrifying similarities between embryonic and metastatic cells.