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Science  07 Mar 2003:
Vol. 299, Issue 5612, pp. 1505-1508
DOI: 10.1126/science.299.5612.1505

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Summary

BOSTON, MASSACHUSETTS-- Researchers have known for nearly 20 years that the AIDS virus gains a huge evolutionary advantage by targeting immune system cells that the body sends out to defeat it. Now new studies presented here last month during the largest annual U.S. AIDS conference provide fresh insights into how the virus has deftly adapted to humans, hijacking, mimicking, and dodging defenses that otherwise might keep it at bay.

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