Relieving DELLA Restraint

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Science  21 Mar 2003:
Vol. 299, Issue 5614, pp. 1853-1854
DOI: 10.1126/science.1083217

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Phytohormones such as gibberellins are known to promote plant growth, but it is unclear how they do this. In a Perspective, Harberd discusses new work ( Sasaki et al. ) that reveals the biochemical basis of the relief-of-restraint model of plant growth regulation. A gibberellin signal promotes proteasomal degradation of DELLA proteins, which normally restrain plant growth.