May the Force Be with You

Science  04 Apr 2003:
Vol. 300, Issue 5616, pp. 63-65
DOI: 10.1126/science.1084148

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Much is known about the reorganization of cell layers during embryogenesis, but the actual forces exerted as epithelial sheets bend, fold, and tuck during events such as dorsal closure and gastrulation have not yet been elucidated. In their Perspective, Martin and Parkhurst discuss one of the first examples of a study ( Hutson et al.) that seeks to measure the forces exerted in the fruit fly embryo during dorsal closure.