DATABASE: Secrets of Slime

Science  18 Apr 2003:
Vol. 300, Issue 5618, pp. 399a
DOI: 10.1126/science.300.5618.399a

Although the slime mold Dictyostelium has no limbs or organs, it has become a favorite for studying the molecular workings of a host of human diseases. For example, researchers probing this blob discerned how cells develop resistance to the anticancer drug cisplatin. This new site, curated by T. B. K. Reddy of the San Diego Supercomputer Center, oozes with data on some 1400 slime mold proteins whose human equivalents are linked to diseases. For each protein, you can find out basic stats, such as the length of its gene; look up functional information; and locate kindred proteins in other model organisms. The database is the latest outgrowth from the Supercomputer Center's site on Dictyostelium genomics (Science, 31 August 2001, p. 1563).

Navigate This Article