PerspectiveSignal Transduction

Autoinhibition Control

+ See all authors and affiliations

Science  02 May 2003:
Vol. 300, Issue 5620, pp. 750-752
DOI: 10.1126/science.1082024

You are currently viewing the summary.

View Full Text

Via your Institution

Log in through your institution

Log in through your institution


Summary

How do receptor tyrosine kinases hold their kinase activity in check until the receptor is activated by its ligand? As Schlessinger explains in his Perspective, receptor tyrosine kinases have evolved several elegant mechanisms to keep kinase activity at bay until the receptor binds to its ligand.

Related Content