PerspectiveBiomedicine

A View from the Top--Prion Diseases from 10,000 Feet

Science  09 May 2003:
Vol. 300, Issue 5621, pp. 917-919
DOI: 10.1126/science.1085920

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Summary

The transmissible spongiform encephalopathies or prion diseases include scrapie in sheep, mad cow disease, and variant Creutzfeld-Jakob disease in humans. The agent of all of these diseases is thought to be a self-replicating protein or prion. In a report of a recent meeting on prion diseases, Priola, Chesebro, and Caughey discuss the latest developments in this often contentious field of research.