PerspectiveMolecular Biology

SMC Complexes--Wrapped Up in Controversy

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Science  16 May 2003:
Vol. 300, Issue 5622, pp. 1101-1102
DOI: 10.1126/science.1084478

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SMC proteins regulate key chromosomal events during cell division. In their Perspective, Milutinovich and Koshland discuss several papers published here ( Kitajima et al.) and elsewhere that elucidate how SMC proteins, in complexes with their binding partners, bind to chromatin to carry out their many functions.