News of the WeekBehavioral Genetics

Getting the Short End of the Allele

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Science  18 Jul 2003:
Vol. 301, Issue 5631, pp. 291-293
DOI: 10.1126/science.301.5631.291a

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On page 386, scientists identify a version of a gene that plays a small but significant role in whether or not people get depressed in response to life stresses. The gene in question is for a chemical transporter that fine-tunes transmission of serotonin, the neurotransmitter affected by the antidepressant Prozac and others of its ilk.