News FocusNeuroscience

Depression Drugs' Powers May Rest on New Neurons

Science  08 Aug 2003:
Vol. 301, Issue 5634, pp. 757
DOI: 10.1126/science.301.5634.757

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Blocking neurogenesis in adult mice renders antidepressants ineffective, lending support to a theory that a dearth of newborn neurons contributes to depression. Work described on page 805 provides some of the best evidence to date that changes in neurogenesis might at least partly explain how the disease progresses.