PerspectiveCircadian Rhythms

Liver Regeneration Clocks On

Science  10 Oct 2003:
Vol. 302, Issue 5643, pp. 234-235
DOI: 10.1126/science.1090810

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In some simple protozoans and unicellular algae, the cell cycle clock is strongly influenced by the circadian clock, such that mitotic cell division takes place only at certain times of the day. Now, as Schibler reports in his Perspective, new work on regenerating liver cells in mice ( Matsuo et al.) reveals that the cell cycle clock of mammalian cells is also under the yoke of the master circadian oscillator.