A Risky Business--Assessing Breast Cancer Risk

See allHide authors and affiliations

Science  24 Oct 2003:
Vol. 302, Issue 5645, pp. 574-575
DOI: 10.1126/science.1091465

You are currently viewing the summary.

View Full Text

Log in to view the full text

Log in through your institution

Log in through your institution


An analysis of BRCA1 and BRCA2 mutations in female relatives of carriers identified among 1008 breast cancer patients has provided revised estimates for the breast cancer risk associated with these mutations. In a Perspective, Levy-Lahad and Plon discuss these revised estimates reported by the New York Breast Cancer Study ( King et al .) and what they reveal about the influence of nongenetic factors on breast cancer susceptibility.