DATABASE: Antiviral Armory

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Science  31 Oct 2003:
Vol. 302, Issue 5646, pp. 757
DOI: 10.1126/science.302.5646.757c

A new online database from the National Institute of Allergy and Infectious Diseases profiles more than 100,000 compounds tested against HIV or the pathogens that exploit AIDS patients' faltering immunity. The site draws on information plucked from papers, conference abstracts, and other sources. Each entry supplies the compound's chemical structure, PubMed references, and other facts, such as the company or lab developing it. Profiled chemicals range from the protease inhibitor lactacystin to a compound called HIP, which might suppress AIDS-related cancer. Smaller linked databases let you glean results from studies of molecules aimed at particular viral enzymes, opportunistic infections, and cell types.

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