PerspectiveEvolution

Heirlooms in the Attic

See allHide authors and affiliations

Science  07 Nov 2003:
Vol. 302, Issue 5647, pp. 997-999
DOI: 10.1126/science.1092271

You are currently viewing the summary.

View Full Text

Log in to view the full text

Log in through your institution

Log in through your institution

Summary

As the human genome was being sequenced, many people suggested just sequencing protein-coding regions because the rest of the genome is "junk" DNA. As Johnston and Stormo explain in their Perspective, thankfully those who advocated sequencing the entire genome did us all a big service. It turns out that a surprising proportion of the so-called junk DNA is highly conserved ( Dermitzakis et al .), suggesting that even though it is noncoding DNA, it does have important functions that have yet to be elucidated.