DATABASE: A Map of Human Variation

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Science  21 Nov 2003:
Vol. 302, Issue 5649, pp. 1305
DOI: 10.1126/science.302.5649.1305c

A project to map how humankind varies genetically has unveiled its Web site, along with a first batch of data. The International HapMap Project is making a “haplotype map” of common patterns of variation by examining mutations in the DNA of 270 people of European, Nigerian, Japanese, and Chinese descent (Science, 1 November 2002, p. 941). The public data should be a boon to researchers looking for genes that make people susceptible to disease or side effects from drugs.

A year into the 3-year project, the HapMap Project on 1 November released over 13 million genotypes from 145,554 mutations, known as SNPs. You can browse alleles for mutation frequencies, or get genotype data for individuals by registering and agreeing to conditions, such as not patenting the data. In the coming months, the site will add material to explain the HapMap to the public.

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