PerspectiveMolecular Biology

Ring Around the Retroelement

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Science  09 Jan 2004:
Vol. 303, Issue 5655, pp. 182-184
DOI: 10.1126/science.1093514

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Molecular biologists have long been intrigued by mobile DNA elements in the genome called retrotransposons and how they replicate and become inserted at new chromosomal sites. New insights into how branching and debranching of retrotransposon transcripts may contribute to this process (Cheng and Menees) are discussed by Perlman and Boeke in their Perspective.