PerspectiveStructural Biology

Surprising News from the PCC

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Science  16 Jan 2004:
Vol. 303, Issue 5656, pp. 320-322
DOI: 10.1126/science.1094664

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It is well established that a protein-conducting channel enables hydrophilic secretory proteins to be translocated across membranes and hydrophobic membrane proteins to be inserted into lipid bilayers. In their Perspective, Dobberstein and Sinning discuss a new structural study (published elsewhere) that reveals the molecular mechanism of protein translocation in bacteria and eukaryotes.