The Robin Hood of Antigen Presentation

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Science  23 Jan 2004:
Vol. 303, Issue 5657, pp. 485-487
DOI: 10.1126/science.1093953

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Immunologists continue to unveil a startling diversity in the antigenic repertoire of T cells, which now rivals that of B cells. In his Perspective, De Libero discusses new work ( Zhou et al., Moody et al.) that adds lipopeptide antigens to the list of T cell immunogens and reveals how lipid antigens are handled in antigen-presenting cells and then presented to T cells.