PerspectiveDevelopmental Biology

A Pattern of Precision

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Science  30 Jan 2004:
Vol. 303, Issue 5658, pp. 637-638
DOI: 10.1126/science.1094409

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The nematode is a simple organism that has proved invaluable for studying cell fate decisions during development. In his Perspective, Sternberg discusses new work ( Yoo et al. ) showing that cooperation between the EGF and LIN-12 signaling pathways determines the fates adopted by vulval precursor cells during vulval development in the nematode.