DATABASE: Genomes United

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Science  06 Feb 2004:
Vol. 303, Issue 5659, pp. 739
DOI: 10.1126/science.303.5659.739b

Scientists have sequenced the genomes of more than 150 organisms, and they polish off a new one about every week. But comparing these results can be a headache because the data are stashed on multiple Web sites that use different formats and sometimes even different names for the same proteins. Bringing order to this genomic tower of Babel is Cogent, a central storehouse from the European Bioinformatics Institute in Cambridge, U.K. Here, visitors can download a list of predicted proteins for every completed genome, from ours (the 45th sequenced) to that of Yersinia pestis, the bacterium responsible for bubonic plague (number 64). Moreover, the database's standard nomenclature and organization makes it easier to contrast different species.

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