PerspectiveDevelopment

Making Sense of the Sensory Lineage

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Science  13 Feb 2004:
Vol. 303, Issue 5660, pp. 966-968
DOI: 10.1126/science.1094732

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Summary

Neural crest cells are multipotent stem cell-like precursors that give rise to many different cell types in the developing embryo. In her Perspective, Bronner-Fraser discusses new research ( Lee et al.) that identifies the Wnt signaling pathway as the developmental instruction directing neural crest cells to become sensory neurons.