PerspectiveMolecular Biology

Filling Gaps in Genome Organization

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Science  20 Feb 2004:
Vol. 303, Issue 5661, pp. 1148-1149
DOI: 10.1126/science.1095356

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Summary

Dosage compensation is a mechanism that redresses the X chromosome imbalance between males and females by reducing gene expression from the whole X chromosome. In their Perspective, Alekseyenko and Kuroda discuss new research in the nematode ( Csankovszki et al.) that follows the movements of the protein complex responsible for X chromosome repression in this organism.