IMMUNOLOGY: After the Toll Rush

Science  05 Mar 2004:
Vol. 303, Issue 5663, pp. 1481-1482
DOI: 10.1126/science.1096113

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The family of Toll-like receptors have garnered much interest because of their ability to detect bacterial and viral molecules and to activate the innate immune response. In his Perspective, O'Neill introduces a trio of papers ( Zhang et al., Heil et al., and Diebold et al.) that provide new information about how Toll-like receptors activate innate immunity.

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