Shotgun Sequencing in the Sea: A Blast from the Past?

Science  02 Apr 2004:
Vol. 304, Issue 5667, pp. 58-60
DOI: 10.1126/science.1097146

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The enormous microbial diversity in the world's oceans is only starting to be explored. In their Perspective, Falkowski and de Vargas discuss a major effort using high-throughput DNA sequencing and computational genomics to identify all of the microbes in 1500 liters of surface seawater from the North Atlantic ( Venter et al.).