Developing an AIDS Vaccine: Need, Uncertainty, Hope

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Science  25 Jun 2004:
Vol. 304, Issue 5679, pp. 1913-1914
DOI: 10.1126/science.1100368

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It is more than 20 years since the identification of HIV, the virus that causes AIDS. In their Perspective, Emini and Koff discuss how far we have come in understanding the interaction of HIV with the host immune system, and what we must learn to develop an effective vaccine that will halt the spread of AIDS.