PerspectiveCell Biology

Double Membrane Fusion

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Science  17 Sep 2004:
Vol. 305, Issue 5691, pp. 1723-1724
DOI: 10.1126/science.1104244

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Mitochondria are highly dynamic organelles that undergo fusion and fission continuously as they partake in functions as varied as bioenergetics, apoptosis, and the differentiation of cells. In their Perspective, Pfanner et al. discuss development of a new in vitro assay that has enabled the intermediate steps in the fusion between two mitochondria to be analyzed in detail ( Meeusen et al.).