News of the WeekGenetics

Disease Backs Cancer Origin Theory

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Science  15 Oct 2004:
Vol. 306, Issue 5695, pp. 389
DOI: 10.1126/science.306.5695.389a

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A study published online in Nature Genetics this week provides the strongest evidence yet that DNA repair defects are the starting gun for cancer and not merely a consequence of it by showing that mutations in a gene involved in ensuring proper chromosome number result in childhood cancer.