TOOLS: Protein Sorter

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Science  12 Nov 2004:
Vol. 306, Issue 5699, pp. 1109
DOI: 10.1126/science.306.5699.1109c

Proteomic and genomic experiments pour out long lists of proteins. Researchers who need help comparing these proteins and figuring out what they do can open PANDORA, a protein-clustering tool hosted by the Hebrew University of Jerusalem in Israel. Users enter the proteins from their experiment, and then PANDORA gathers descriptions of the entries from other databases and uses them to parcel the molecules into smaller groups. The procedure “grabs the big picture,” says co-creator Michal Linial of Hebrew University. For example, proteins that clump together in the analysis may also work together to perform a specific task or may congregate in the cell.

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