Policy ForumMolecular Biology

NIH Molecular Libraries Initiative

Science  12 Nov 2004:
Vol. 306, Issue 5699, pp. 1138-1139
DOI: 10.1126/science.1105511

You are currently viewing the summary.

View Full Text

Via your Institution

Log in through your institution

Log in through your institution


Summary

The Molecular Libraries Initiative (MLI) of the NIH Roadmap for Medical Research is a bold set of programs to facilitate the use of small molecules in the public sector and expand the reach of small-molecule technologies to define gene, cell, and organism function in health and disease. The initiative described in this Policy Forum has three components: the Molecular Libraries Screening Centers Network; cheminformatics initiatives including a new public compound database (PubChem); and technology development initiatives in chemical diversity, cheminformatics, assay development, screening instrumentation, and predictive ADMET. All research tools and results will be made publicly available without encumbrance. The small-molecule tools and technologies produced by the MLI will accelerate gene function determination, target validation, and downstream drug development.

Related Content