Contents
Vol 307, Issue 5707
Contents
This Week in Science
Editorial
Editors' Choice
NetWatch
Departments
Products & Materials
News of the Week
ScienceScope
Random Samples
News Focus
Letters
Books
Policy Forum
Perspectives
Review
Brevia
- The First Glacial Maximum in North America
Cosmic ray dating of glacial deposits in Missouri shows that one of the first large Northern Hemisphere ice sheets extended that far south 2.4 million years ago.
Research Article
- A Diarylquinoline Drug Active on the ATP Synthase of Mycobacterium tuberculosis
A high-potency antibiotic that acts through a different pathway than do existing drugs kills tuberculosis-causing microbes effectively (including resistant ones) and is safe for humans.
Reports
- Time-Domain Measurements of Nanomagnet Dynamics Driven by Spin-Transfer Torques
Injection of electrons with specific spins into a nanomagnet can induce the magnetic moment to precess or even reverse.
- Al Cluster Superatoms as Halogens in Polyhalides and as Alkaline Earths in Iodide Salts
Large clusters of aluminum and iodine atoms act like individual superhalogen or alkali-earth atoms and drive the outcome of chemical reactions.
- A Stable Aminyl Radical Metal Complex
An otherwise highly reactive molecule bearing an electron-deficient nitrogen atom is stabilized by coordination to rhodium.
- Encapsulation of Molecular Hydrogen in Fullerene C60 by Organic Synthesis
A fullerene derivative contains a 13-membered ring that can be opened and closed in four reaction steps to create new molecules with hydrogen or other gases trapped within C60.
- Corrected Late Triassic Latitudes for Continents Adjacent to the North Atlantic
A model reveals the latitudes at which sedimentary rocks formed by accounting for the rotation of the past direction of Earth's magnetic field preserved in the rocks.
- An Astronomical 2175 Å Feature in Interplanetary Dust Particles
Laboratory spectra of organic carbon and amorphous silica grains found in dust particles from space resemble and can explain the enigmatic spectra of ubiquitous interstellar dust.
- Retinoic Acid Signaling Restricts the Cardiac Progenitor Pool
A hormone that controls many of the later steps in heart formation also acts early in development to determine the number of cells in the heart and thus its ultimate size.
- Global Circumnavigations: Tracking Year-Round Ranges of Nonbreeding Albatrosses
Tracking of albatrosses shows that some circumnavigate the globe in less than two months, whereas others wander to the Indian Ocean or near their breeding area.
- No Transcription-Translation Feedback in Circadian Rhythm of KaiC Phosphorylation
In cyanobacteria, cycling of a component of the circadian clock is driven by its periodic phosphorylation, not by periodic transcription or translation as in other species.
- CX3CR1-Mediated Dendritic Cell Access to the Intestinal Lumen and Bacterial Clearance
A specialized receptor for a hormone is required for immune cells in the gut to sample the intestinal contents and provide protection from pathogenic bacteria.
- Anticonvulsant Medications Extend Worm Life-Span
Drugs used to treat human seizures also retard the aging process in adult worms, suggesting an approach to delay aging in humans.
- Self-Propagating, Molecular-Level Polymorphism in Alzheimer's ß-Amyloid Fibrils
The amyloid associated with Alzheimer's disease has properties reminiscent of prion proteins, forming fibrils with distinct heritable structures and different toxicities.
- Semaphorin 3E and Plexin-D1 Control Vascular Pattern Independently of Neuropilins
A mouse guidance molecule requires two coreceptors to direct neuronal development but only one to sculpt the vasculature.
- Stat3 Dimerization Regulated by Reversible Acetylation of a Single Lysine Residue
Transcription factors known to be regulated by phosphorylation can also be modified by acetylation, which activates cytokine production via dimerization.
