Harvesting Medical Information from the Human Family Tree

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Science  18 Feb 2005:
Vol. 307, Issue 5712, pp. 1052-1053
DOI: 10.1126/science.1109682

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Working with 71 individuals from three diverse human populations, Hinds et al. have characterized more than 1.5 million individual differences in human DNA sequences. In a Perspective, Altshuler and Clark discuss the significance of these findings, their correlation with data from the International Haplotype Map Project, and what both data sets mean for understanding complex human diseases caused by multiple factors.