DATABASE: Genetics of Seizures

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Science  25 Feb 2005:
Vol. 307, Issue 5713, pp. 1177
DOI: 10.1126/science.307.5713.1177b

The new database CarpeDB profiles some 400 genes linked to epilepsy in humans, mice, nematodes, and other organisms. Cody Locke, an undergraduate working with neurobiologists Guy and Kim Caldwell at the University of Alabama, Tuscaloosa, compiled the collection for researchers studying the genetics of epilepsy and related conditions. Pick a gene such as ENFL2, which triggers nocturnal seizures, and you'll summon a virtual index card listing the gene's chromosomal location, the condition it contributes to, references, and other data. For further information, follow links to sites such as Online Mendelian Inheritance in Man and UniProt.

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