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Science  18 Mar 2005:
Vol. 307, Issue 5716, pp. 1712-1715
DOI: 10.1126/science.307.5716.1712

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Summary

LEBANON, NEW HAMPSHIRE-- Converting an idea for a new multiple sclerosis drug into the real thing turns out to be much harder than a pair of Dartmouth researchers ever imagined--but they refuse to let it go.