IMAGES: Neurons on Display

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Science  25 Mar 2005:
Vol. 307, Issue 5717, pp. 1847
DOI: 10.1126/science.307.5717.1847a

The Cell Centered Database from the University of California, San Diego, is a destination for everyone from anatomists charting the nuances of neuron branching to modelers hoping to devise more realistic cell simulations. Launched in 2002, the archive houses images, reconstructions, and models of nerve cells of brain neurons based on microscopy data, including confocal and electron. The site helps fill the gap between gene and protein databases and those holding images of larger brain structures, says project leader Maryann Martone. Visitors can access images and raw data on more than 30 nervous system cells. Included, for instance, is an image in which the colors indicate the different dendrite segments in a Purkinje neuron from a rat's cerebellum. The listings also include measurements such as the cell's surface area and the lengths of major branches. So far the archive only encompasses nerve cells, but Martone and colleagues will soon add mitochondrial data.

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