PerspectiveMolecular Biology

Signal Processing in Single Cells

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Science  25 Mar 2005:
Vol. 307, Issue 5717, pp. 1886-1888
DOI: 10.1126/science.1110797

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Gene networks can be designed that enable exploration of how gene expression is regulated, an example of synthetic biology. In their Perspective, Isaacs et al. discuss two studies ( Rosenfeld et al., Pedraza and van Oudenaarden) that combine modeling with experiments to analyze gene networks in bacteria.