Report

Comparison of Fine-Scale Recombination Rates in Humans and Chimpanzees

Science  01 Apr 2005:
Vol. 308, Issue 5718, pp. 107-111
DOI: 10.1126/science.1105322

You are currently viewing the abstract.

View Full Text

Via your Institution

Log in through your institution

Log in through your institution


Abstract

We compared fine-scale recombination rates at orthologous loci in humans and chimpanzees by analyzing polymorphism data in both species. Strong statistical evidence for hotspots of recombination was obtained in both species. Despite ∼99% identity at the level of DNA sequence, however, recombination hotspots were found rarely (if at all) at the same positions in the two species, and no correlation was observed in estimates of fine-scale recombination rates. Thus, local patterns of recombination rate have evolved rapidly, in a manner disproportionate to the change in DNA sequence.

    View Full Text

    Cited By...