PerspectiveCell Biology

A Fishing Buddy for Hypothesis Generators

See allHide authors and affiliations

Science  22 Apr 2005:
Vol. 308, Issue 5721, pp. 504-506
DOI: 10.1126/science.1110535

You are currently viewing the summary.

View Full Text

Log in to view the full text

Log in through your institution

Log in through your institution

Summary

Understanding how signaling proteins interact in a giant intracellular network to control numerous cellular processes is the goal of many biologists. In their Perspective, Brent and Lok discuss a study that takes us a step closer to accomplishing this goal. The Perspective authors describe the application of Bayesian networks and computational methods to elucidating interactions among the signaling proteins in individual human T cells ( Sachs et al.)