Matching at the Synapse

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Science  06 May 2005:
Vol. 308, Issue 5723, pp. 800-801
DOI: 10.1126/science.1112623

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Neurons in the brain make many thousands of connections (synapses) with other neurons. In a Perspective, Thompson discusses a technical tour-de-force (Koester and Johnson) that reveals subtle differences in the characteristics of neurotransmitter release, which depend on the type of postsynaptic target cells with which the presynaptic cell connects.