PerspectiveMolecular Biology

A Renewed Focus on Transfer RNA

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Science  20 May 2005:
Vol. 308, Issue 5725, pp. 1123-1124
DOI: 10.1126/science.1113415

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Decoding of the genetic message involves both the ribosome and its tRNA substrates. Most studies on the details of this process have focused on the role of the ribosome. In their Perspective, Daviter et al. discuss new work (Cochella and Green) that shows how the properties of tRNA influence its own selection.