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Science  17 Jun 2005:
Vol. 308, Issue 5729, pp. 1740
DOI: 10.1126/science.308.5729.1740b

The Report “Defective Transcription-coupled repair of oxidative base damage in Cockayne syndrome patients from XP group G” (1) is retracted. An ad hoc investigatory committee at the University of North Carolina at Chapel Hill has found that the last author (S.A.L.) of the paper “fabricated and falsified research findings” from an immunological assay for transcription-coupled repair. Three papers that were the subject of the investigation have been retracted. Although this paper was not implicated by the investigation, examination of the original data for Figs. 1 and 3 by P.K.C. indicates that the results of these experiments are not valid as reported in Science. Although some findings in the paper, notably those of Fig. 2, have been verified, the overall integrity of the paper cannot be supported by the presented results. We are therefore retracting the paper. The first three authors of the paper were not cognizant of any irregularities and were not involved in any wrongdoing. The fourth author (S.A.L.) declined to sign this retraction.


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