Translocation of Anthrax Toxin: Lord of the Rings

Science  29 Jul 2005:
Vol. 309, Issue 5735, pp. 709-710
DOI: 10.1126/science.1116630

You are currently viewing the summary.

View Full Text

Via your Institution

Log in through your institution

Log in through your institution


[HN11] Many microorganisms have evolved ingenious ways of shipping toxic proteins into target cells. In his Perspective, von Heijne discusses a study by Krantz et al. that reveals how anthrax toxin gets into a cell. A ring of aromatic amino acids in a pore formed by anthrax toxin helps unfold other anthrax toxin proteins and facilitate their translocation across the cell membrane.