News of the WeekGenetics

Mouse With Human Chromosome Should Boost Down Syndrome Research

Science  23 Sep 2005:
Vol. 309, Issue 5743, pp. 1975
DOI: 10.1126/science.309.5743.1975a

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On page 2033 of this issue of Science, researchers report creating a strain of mice with a nearly complete copy of human chromosome 21. The strain's unusual genome mimics the genetic makeup of people with Down syndrome, the most common inherited form of mental retardation.