DATABASE: Molecular Pick Ax

See allHide authors and affiliations

Science  30 Sep 2005:
Vol. 309, Issue 5744, pp. 2141
DOI: 10.1126/science.309.5744.2141b

Knocking out genes is one way to decipher their function. Another method that's gaining popularity is chemical genomics: using small molecules to tweak biochemical pathways. To help researchers sift candidates for these experiments, the site ChemMine from the University of California, Riverside, profiles more than 2 million compounds from commercial suppliers and public databases such as the National Institutes of Health's PubChem. ChemMine's selling point is its many tools. You can track down molecules by structure, chemical properties, and activity; tease out similar compounds; and cluster the results by similarity.

Navigate This Article