Special Reviews

Exploring and Engineering the Cell Surface Interface

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Science  18 Nov 2005:
Vol. 310, Issue 5751, pp. 1135-1138
DOI: 10.1126/science.1106587

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Cells are inherently sensitive to local mesoscale, microscale, and nanoscale patterns of chemistry and topography. We review current approaches to control cell behavior through the nanoscale engineering of materials surfaces. Far-reaching implications are emerging for applications including medical implants, cell supports, and materials that can be used as instructive three-dimensional environments for tissue regeneration.

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