TOOLS: Scourge of a Continent

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Science  23 Dec 2005:
Vol. 310, Issue 5756, pp. 1877
DOI: 10.1126/science.310.5756.1877e

HIV is hammering Africa, with infection rates of more than 30% in countries such as Botswana. Researchers will find tools for analyzing HIV molecular data and information on the main African strain at BioAfrica, created by virologists at Oxford University and the University of Pretoria in South Africa. BioAfrica complements other HIV sites, such as the sequence bank at Los Alamos National Lab in New Mexico (NetWatch, 23 August 2002, p. 1243), by spotlighting HIV's subtype C, the viral variant that predominates in the southern part of the continent. Users can download free software for determining a virus's subtype or visit a new proteomics section that probes the sequences and structures of HIV's 19 proteins. The site also includes plenty of background on subtype C, including charts that follow its spread starting in the early 1980s.

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