IMAGES: Genes at Work

See allHide authors and affiliations

Science  13 Jan 2006:
Vol. 311, Issue 5758, pp. 153
DOI: 10.1126/science.311.5758.153a

GenePaint displays portraits of activity levels for more than 1000 mouse genes involved in development and other functions. The gene expression atlas from the Max Planck Institute of Experimental Endocrinology in Hannover, Germany, holds a complete set of slices from a 14-day-old embryo and selected images for other pre- and postnatal stages. Researchers used probes that tag messenger RNA to indicate each gene's activity level in the slices. You can find out which genes are cranking away in a specific organ system or in about 100 structures, such as the lens of the eye. You can also search the data by expression patterns, including whether a particular gene's activity is local or widespread. A virtual microscope lets users zoom in on a slice down to the cellular level. The site also offers anatomy guides that feature labeled sections such as the head of a 15-day-old embryo.

Navigate This Article