PerspectiveSystems Biology

When Proteomes Collide

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Science  13 Jan 2006:
Vol. 311, Issue 5758, pp. 187-188
DOI: 10.1126/science.1123221

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Although the protein interaction network of herpesvirus does not resemble that of its human host, it merges at multiple points with the human network during infection. Such a strategy may optimize conditions for establishing a pathogenic state.